3I4N

8-oxoguanine containing RNA polymerase II elongation complex E

3I4N の概要

• エントリーDOI: 10.2210/pdb3i4n/pdb
• 関連するPDBエントリー: 3I4M
• 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11, ... (17 entities in total)
• 機能のキーワード: rna polymerase ii, metal-binding, transcription bubble, elongation complex, transcription, 8-oxoguanine, dna damage, oxidative damage, dna-binding, dna-directed rna polymerase, isopeptide bond, magnesium, nucleotidyltransferase, nucleus, phosphoprotein, transferase, zinc-finger, dna repair, mrna processing, transferase-dna-rna hybrid complex, transferase/dna-rna hybrid
• 由来する生物種: Saccharomyces cerevisiae (baker's yeast); 詳細
• 細胞内の位置: Nucleus: P04050 P38902 P08518 P16370 P20433 P20434 P34087 P20436 P27999; Nucleus, nucleolus: P22139 P40422; Cytoplasm: P20435
• タンパク質・核酸の鎖数: 15
• 化学式量合計: 532306.12

構造登録者

Damsma, G.E.,Cramer, P. (登録日: 2009-07-02, 公開日: 2009-09-08, 最終更新日: 2023-11-01)

• 主引用文献: Damsma, G.E.,Cramer, P.; Molecular basis of transcriptional mutagenesis at 8-oxoguanine; J.Biol.Chem., 284:31658-31663, 2009; PubMed: 19758983; DOI: 10.1074/jbc.M109.022764

実験手法

X-RAY DIFFRACTION (3.9 Å)