3I2T

Crystal structure of the unliganded Drosophila Epidermal Growth Factor Receptor ectodomain

3I2T の概要

• エントリーDOI: 10.2210/pdb3i2t/pdb
• 分子名称: Epidermal growth factor receptor, isoform A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: drosophila, egfr, ectodomain, unliganded, autoinhibited, atp-binding, nucleotide-binding, tyrosine-protein kinase, transferase
• 由来する生物種: Drosophila melanogaster (Fruit fly)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 65060.16

構造登録者

Alvarado, D.,Klein, D.E.,Lemmon, M.A. (登録日: 2009-06-29, 公開日: 2009-09-08, 最終更新日: 2023-09-06)

• 主引用文献: Alvarado, D.,Klein, D.E.,Lemmon, M.A.; ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor.; Nature, 461:287-291, 2009; PubMed: 19718021; DOI: 10.1038/nature08297

実験手法

X-RAY DIFFRACTION (2.7 Å)