3I29

Crystal structure of a binary complex between an mutant trypsin inhibitor with bovine trypsin

3I29 の概要

• エントリーDOI: 10.2210/pdb3i29/pdb
• 関連するPDBエントリー: 2QYI 3I2A 3I2X
• 分子名称: Cationic trypsin, Chymotrypsin inhibitor 3, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: p1 and p2 mutant, trypsin inhibitor, bovine trypsin, complex, digestion, hydrolase, metal-binding, protease, secreted, serine protease, zymogen, protease inhibitor, serine protease inhibitor, hydrolase-hydrolase inhibitor complex, disulfide bond, hydrolase/hydrolase inhibitor
• 由来する生物種: Bos taurus (bovine); 詳細
• 細胞内の位置: Secreted, extracellular space: P00760
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 44104.72

構造登録者

Khamrui, S.,Majumder, S.,Dasgupta, J.,Dattagupta, J.K.,Sen, U. (登録日: 2009-06-29, 公開日: 2010-06-16, 最終更新日: 2023-11-01)

• 主引用文献: Majumder, S.,Khamrui, S.,Dasgupta, J.,Dattagupta, J.K.,Sen, U.; Role of remote scaffolding residues in the inhibitory loop pre-organization, flexibility, rigidification and enzyme inhibition of serine protease inhibitors; Biochim.Biophys.Acta, 1824:882-890, 2012; PubMed: 22709512; DOI: 10.1016/j.bbapap.2012.04.009

実験手法

X-RAY DIFFRACTION (2.4 Å)