3HYM

Insights into Anaphase Promoting Complex TPR subdomain assembly from a CDC26-APC6 structure

Summary for 3HYM

Entry DOI	10.2210/pdb3hym/pdb
Descriptor	Anaphase-promoting complex subunit CDC26, Cell division cycle protein 16 homolog (3 entities in total)
Functional Keywords	apc, anaphase promoting complex, cell cycle, mitosis, cyclosome, tpr, ubiquitin, ubiquitin ligase, e3, twinning, alternative splicing, cell division, phosphoprotein, tpr repeat, ubl conjugation pathway, coiled coil, nucleus, ligase
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm, cytoskeleton, centrosome: Q8NHZ8 Nucleus (By similarity): Q13042
Total number of polymer chains	12
Total formula weight	249117.64
Authors	Wang, J.,Dye, B.T.,Rajashankar, K.R.,Kurinov, I.,Schulman, B.A. (deposition date: 2009-06-22, release date: 2009-08-11, Last modification date: 2011-07-13)
Primary citation	Wang, J.,Dye, B.T.,Rajashankar, K.R.,Kurinov, I.,Schulman, B.A. Insights into anaphase promoting complex TPR subdomain assembly from a CDC26-APC6 structure. Nat.Struct.Mol.Biol., 16:987-989, 2009 Cited by PubMed: 19668213 DOI: 10.1038/nsmb.1645 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation