3HY8

Crystal Structure of Human Pyridoxine 5'-Phosphate Oxidase R229W Mutant

3HY8 の概要

• エントリーDOI: 10.2210/pdb3hy8/pdb
• 分子名称: Pyridoxine-5'-phosphate oxidase, FLAVIN MONONUCLEOTIDE, PYRIDOXAL-5'-PHOSPHATE, ... (5 entities in total)
• 機能のキーワード: fmn binding protein, oxidase, disease mutation, epilepsy, flavoprotein, fmn, oxidoreductase, phosphoprotein, pyridoxal phosphate, pyridoxine biosynthesis
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 31046.44

構造登録者

Safo, M.K.,Musayev, F.N.,Di Salvo, M.L.,Saavedra, M.K.,Schirch, V. (登録日: 2009-06-22, 公開日: 2009-07-28, 最終更新日: 2023-09-06)

• 主引用文献: Musayev, F.N.,Di Salvo, M.L.,Saavedra, M.A.,Contestabile, R.,Ghatge, M.S.,Haynes, A.,Schirch, V.,Safo, M.K.; Molecular basis of reduced pyridoxine 5'-phosphate oxidase catalytic activity in neonatal epileptic encephalopathy disorder; J.Biol.Chem., 284:30949-30956, 2009; PubMed: 19759001; DOI: 10.1074/jbc.M109.038372

実験手法

X-RAY DIFFRACTION (2.5 Å)