3HWT

Ternary complex of DNA polymerase lambda bound to a two nucleotide gapped DNA substrate with a scrunched dA

3HWT の概要

• エントリーDOI: 10.2210/pdb3hwt/pdb
• 関連するPDBエントリー: 3HW8 3HX0
• 分子名称: DNA polymerase lambda, 5'-D(*CP*GP*GP*CP*AP*AP*AP*TP*AP*CP*TP*G)-3', 5'-D(*CP*AP*GP*TP*AP*(2DT))-3', ... (9 entities in total)
• 機能のキーワード: helix-hairpin-helix, dna damage, dna repair, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, lyase, manganese, metal-binding, nucleotidyltransferase, nucleus, phosphoprotein, transferase, transferase-dna complex, transferase/dna
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus : Q9UGP5
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 44678.69

構造登録者

Garcia-Diaz, M.,Bebenek, K.,Larrea, A.A.,Pedersen, L.C.,Kunkel, T.A. (登録日: 2009-06-18, 公開日: 2009-08-25, 最終更新日: 2023-09-06)

• 主引用文献: Garcia-Diaz, M.,Bebenek, K.,Larrea, A.A.,Havener, J.M.,Perera, L.,Krahn, J.M.,Pedersen, L.C.,Ramsden, D.A.,Kunkel, T.A.; Scrunching during DNA repair synthesis; To be Published,

実験手法

X-RAY DIFFRACTION (1.95 Å)