3HWJ

Crystal structure of the second PHR domain of Mouse Myc-binding protein 2 (MYCBP-2)

3HWJ の概要

• エントリーDOI: 10.2210/pdb3hwj/pdb
• 関連するPDBエントリー: 3GBW
• 分子名称: E3 ubiquitin-protein ligase MYCBP2, DIMETHYL SULFOXIDE (3 entities in total)
• 機能のキーワード: myc-binding protein 2, mycbp2, phr proteins, phr domain, probable e3 ubiquitin-protein ligase mycbp2, protein associated with myc, pam, phr1, structural genomics, psi-2, protein structure initiative, new york structural genomix research consortium, nysgxrc, alternative splicing, ligase, metal-binding, nucleus, phosphoprotein, transcription, transcription regulation, ubl conjugation pathway, zinc, zinc-finger, new york sgx research center for structural genomics
• 由来する生物種: Mus musculus (mouse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 38181.45

構造登録者

Sampathkumar, P.,Ozyurt, S.A.,Wasserman, S.R.,Miller, S.A.,Bain, K.T.,Rutter, M.E.,Gheyi, T.,Klemke, R.L.,Atwell, S.,Sauder, J.M.,Burley, S.K.,New York SGX Research Center for Structural Genomics (NYSGXRC) (登録日: 2009-06-17, 公開日: 2009-07-21, 最終更新日: 2023-12-27)

• 主引用文献: Sampathkumar, P.,Ozyurt, S.A.,Miller, S.A.,Bain, K.T.,Rutter, M.E.,Gheyi, T.,Abrams, B.,Wang, Y.,Atwell, S.,Luz, J.G.,Thompson, D.A.,Wasserman, S.R.,Emtage, J.S.,Park, E.C.,Rongo, C.,Jin, Y.,Klemke, R.L.,Sauder, J.M.,Burley, S.K.; Structures of PHR domains from Mus musculus Phr1 (Mycbp2) explain the loss-of-function mutation (Gly1092-->Glu) of the C. elegans ortholog RPM-1.; J.Mol.Biol., 397:883-892, 2010; PubMed: 20156452; DOI: 10.1016/j.jmb.2010.02.017

実験手法

X-RAY DIFFRACTION (2.25 Å)