3HSM

Crystal structure of distal N-terminal beta-trefoil domain of Ryanodine Receptor type 1

3HSM の概要

• エントリーDOI: 10.2210/pdb3hsm/pdb
• 分子名称: Ryanodine receptor 1 (2 entities in total)
• 機能のキーワード: beta-trefoil, calcium, calcium channel, calcium transport, glycoprotein, ion transport, ionic channel, membrane, phosphoprotein, receptor, s-nitrosylation, transmembrane, transport, signaling protein
• 由来する生物種: Oryctolagus cuniculus (rabbit)
• 細胞内の位置: Sarcoplasmic reticulum membrane ; Multi-pass membrane protein : P11716
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 46550.46

構造登録者

Amador, F.J.,Liu, S.,Ishiyama, N.,Plevin, M.J.,Wilson, A.,MacLennan, D.H.,Ikura, M. (登録日: 2009-06-10, 公開日: 2009-07-28, 最終更新日: 2023-09-06)

• 主引用文献: Amador, F.J.,Liu, S.,Ishiyama, N.,Plevin, M.J.,Wilson, A.,MacLennan, D.H.,Ikura, M.; Crystal structure of type I ryanodine receptor amino-terminal beta-trefoil domain reveals a disease-associated mutation "hot spot" loop; Proc.Natl.Acad.Sci.USA, 106:11040-11044, 2009; PubMed: 19541610; DOI: 10.1073/pnas.0905186106

実験手法

X-RAY DIFFRACTION (2.5 Å)