3HRR

The Product Template Domain from PksA with Harris Compound Bound

3HRR の概要

• エントリーDOI: 10.2210/pdb3hrr/pdb
• 関連するPDBエントリー: 3HRQ
• 分子名称: Aflatoxin biosynthesis polyketide synthase, 1-(3-acetyl-4,5-dihydroxy-7-methoxynaphthalen-2-yl)propan-2-one (3 entities in total)
• 機能のキーワード: pksa, aflatoxin, norsolorinic acid, polyketide, polyketide synthase, pks, iterative type i pks, harris compound, hot-dog fold, acyltransferase, multifunctional enzyme, phosphopantetheine, transferase, transcription
• 由来する生物種: Aspergillus parasiticus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 79063.68

構造登録者

Korman, T.P.,Tsai, S.C. (登録日: 2009-06-09, 公開日: 2009-10-20, 最終更新日: 2023-09-06)

• 主引用文献: Crawford, J.M.,Korman, T.P.,Labonte, J.W.,Vagstad, A.L.,Hill, E.A.,Kamari-Bidkorpeh, O.,Tsai, S.C.,Townsend, C.A.; Structural basis for biosynthetic programming of fungal aromatic polyketide cyclization.; Nature, 461:1139-1143, 2009; PubMed: 19847268; DOI: 10.1038/nature08475

実験手法

X-RAY DIFFRACTION (1.9 Å)