3HR3
Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Hydrophobic Modifications Better than DNA
Summary for 3HR3
Entry DOI | 10.2210/pdb3hr3/pdb |
Descriptor | 5'-D(*GP*CP*GP*(US4)P*(OMU))P*AP*CP*GP*C)-3' (2 entities in total) |
Functional Keywords | dna, rna, formacetal-dna, rna hydration |
Total number of polymer chains | 1 |
Total formula weight | 3011.05 |
Authors | Egli, M.,Pallan, P.S. (deposition date: 2009-06-08, release date: 2009-10-27, Last modification date: 2023-09-06) |
Primary citation | Kolarovic, A.,Schweizer, E.,Greene, E.,Gironda, M.,Pallan, P.S.,Egli, M.,Rozners, E. Interplay of structure, hydration and thermal stability in formacetal modified oligonucleotides: RNA may tolerate nonionic modifications better than DNA. J.Am.Chem.Soc., 131:14932-14937, 2009 Cited by PubMed: 19824732DOI: 10.1021/ja904926e PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
Download full validation report