3HQM

Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-CiSBC2

Summary for 3HQM

Entry DOI	10.2210/pdb3hqm/pdb
Descriptor	Speckle-type POZ protein, Protein cubitus interruptus, SULFATE ION, ... (4 entities in total)
Functional Keywords	ubiquitin, e3, spop, math, ci, nucleus, ubl conjugation pathway, developmental protein, dna-binding, metal-binding, segmentation polarity protein, zinc-finger, protein binding, ligase
Biological source	Homo sapiens (human)
Cellular location	Nucleus: O43791 P19538
Total number of polymer chains	4
Total formula weight	35966.86
Authors	Zhuang, M.,Schulman, B.A. (deposition date: 2009-06-07, release date: 2009-10-20, Last modification date: 2023-09-06)
Primary citation	Zhuang, M.,Calabrese, M.F.,Liu, J.,Waddell, M.B.,Nourse, A.,Hammel, M.,Miller, D.J.,Walden, H.,Duda, D.M.,Seyedin, S.N.,Hoggard, T.,Harper, J.W.,White, K.P.,Schulman, B.A. Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases. Mol.Cell, 36:39-50, 2009 Cited by PubMed: 19818708 DOI: 10.1016/j.molcel.2009.09.022 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.74 Å)

Structure validation