3HPO
Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus Y714S mutant bound to G:T mismatch
Summary for 3HPO
Entry DOI | 10.2210/pdb3hpo/pdb |
Related | 3HP6 3HT3 |
Related PRD ID | PRD_900003 |
Descriptor | DNA polymerase I, large fragment, 5'-D(*CP*GP*AP*TP*CP*AP*CP*GP*(DOC))-3', 5'-D(P*GP*GP*CP*GP*TP*GP*AP*TP*CP*G)-3', ... (8 entities in total) |
Functional Keywords | protein-dna complex, dna polymerase i, dna replication, dna-binding, dna-directed dna polymerase, hydrolase, nuclease, nucleotidyltransferase, transferase, transferase-dna complex, transferase/dna |
Biological source | Geobacillus stearothermophilus More |
Total number of polymer chains | 3 |
Total formula weight | 72859.51 |
Authors | Wu, E.Y.,Beese, L.S. (deposition date: 2009-06-04, release date: 2010-06-23, Last modification date: 2023-09-06) |
Primary citation | Wu, E.Y.,Beese, L.S. The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism. J.Biol.Chem., 286:19758-19767, 2011 Cited by PubMed: 21454515DOI: 10.1074/jbc.M110.191130 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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