3HOM
Crystal structure of oxidized A66C mutant of Human acidic fibroblast growth factor
Summary for 3HOM
Entry DOI | 10.2210/pdb3hom/pdb |
Related | 1JQZ 3FJK |
Descriptor | Acidic fibroblast growth factor, FORMIC ACID, SULFATE ION, ... (4 entities in total) |
Functional Keywords | beta-trefoil, acetylation, alternative splicing, angiogenesis, developmental protein, differentiation, growth factor, heparin-binding, mitogen, polymorphism, hormone |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P05230 |
Total number of polymer chains | 2 |
Total formula weight | 33625.74 |
Authors | Blaber, M.,Lee, J. (deposition date: 2009-06-02, release date: 2009-10-06, Last modification date: 2023-09-06) |
Primary citation | Lee, J.,Blaber, M. Structural basis of conserved cysteine in the fibroblast growth factor family: evidence for a vestigial half-cystine. J.Mol.Biol., 393:128-139, 2009 Cited by PubMed: 19683004DOI: 10.1016/j.jmb.2009.08.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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