3HLC

Simvastatin Synthase (LovD) from Aspergillus terreus, S5 mutant, unliganded

Summary for 3HLC

• Entry DOI: 10.2210/pdb3hlc/pdb
• Related: 3HL9 3HLB 3HLD
• Descriptor: Transesterase, GLYCEROL, TETRAETHYLENE GLYCOL, ... (4 entities in total)
• Functional Keywords: alpha/beta hydrolase fold, transferase
• Biological source: Aspergillus terreus
• Total number of polymer chains: 1
• Total formula weight: 48449.98

Authors

Sawaya, M.R.,Yeates, T.O.,Laidman, J.,Pashkov, I.,Gao, X.,Tang, Y. (deposition date: 2009-05-27, release date: 2009-10-27, Last modification date: 2024-02-21)

• Primary citation: Gao, X.,Xie, X.,Pashkov, I.,Sawaya, M.R.,Laidman, J.,Zhang, W.,Cacho, R.,Yeates, T.O.,Tang, Y.; Directed evolution and structural characterization of a simvastatin synthase; Chem.Biol., 16:1064-1074, 2009; PubMed: 19875080; DOI: 10.1016/j.chembiol.2009.09.017

Experimental method

X-RAY DIFFRACTION (2 Å)