3HK1

Identification and Characterization of a Small Molecule Inhibitor of Fatty Acid Binding Proteins

3HK1 の概要

• エントリーDOI: 10.2210/pdb3hk1/pdb
• 分子名称: Fatty acid-binding protein, adipocyte, 4-{[2-(methoxycarbonyl)-5-(2-thienyl)-3-thienyl]amino}-4-oxo-2-butenoic acid (3 entities in total)
• 機能のキーワード: lipid binding protein, fatty acid binding protein, cytoplasm, lipid-binding, nucleus, phosphoprotein, transport, protein binding
• 由来する生物種: Mus musculus (mouse)
• 細胞内の位置: Cytoplasm: P04117
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14877.06

構造登録者

Hertzel, A.V.,Hellberg, K.,Reynolds, J.M.,Kruse, A.C.,Juhlmann, B.E.,Smith, A.J.,Sanders, M.A.,Ohlendorf, D.H.,Suttles, J.,Bernlohr, D.A. (登録日: 2009-05-22, 公開日: 2009-09-22, 最終更新日: 2023-09-06)

• 主引用文献: Hertzel, A.V.,Hellberg, K.,Reynolds, J.M.,Kruse, A.C.,Juhlmann, B.E.,Smith, A.J.,Sanders, M.A.,Ohlendorf, D.H.,Suttles, J.,Bernlohr, D.A.; Identification and characterization of a small molecule inhibitor of Fatty Acid binding proteins.; J.Med.Chem., 52:6024-6031, 2009; PubMed: 19754198; DOI: 10.1021/jm900720m

実験手法

X-RAY DIFFRACTION (1.7 Å)