3HHR
HUMAN GROWTH HORMONE AND EXTRACELLULAR DOMAIN OF ITS RECEPTOR: CRYSTAL STRUCTURE OF THE COMPLEX
Replaces: 2HHRSummary for 3HHR
Entry DOI | 10.2210/pdb3hhr/pdb |
Descriptor | HUMAN GROWTH HORMONE, HUMAN GROWTH HORMONE RECEPTOR (hGHbp) (2 entities in total) |
Functional Keywords | hormone/receptor, hormone-receptor complex |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01241 Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Single-pass type I membrane protein. Growth hormone-binding protein: Secreted: P10912 |
Total number of polymer chains | 3 |
Total formula weight | 70012.83 |
Authors | De Vos, A.M.,Ultsch, M.,Kossiakoff, A.A. (deposition date: 1993-12-30, release date: 1994-04-30, Last modification date: 2024-06-05) |
Primary citation | de Vos, A.M.,Ultsch, M.,Kossiakoff, A.A. Human growth hormone and extracellular domain of its receptor: crystal structure of the complex. Science, 255:306-312, 1992 Cited by PubMed: 1549776PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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