3HHP

Malate dehydrogenase open conformation

3HHP の概要

• エントリーDOI: 10.2210/pdb3hhp/pdb
• 分子名称: Malate dehydrogenase (2 entities in total)
• 機能のキーワード: malate dehydrogenase, mdh, citric acid cycle, tca cycle, nad, oxidoreductase, tricarboxylic acid cycle
• 由来する生物種: Escherichia coli K-12
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 129472.70

構造登録者

Zaitseva, J.,Meneely, K.M.,Lamb, A.L. (登録日: 2009-05-15, 公開日: 2009-09-22, 最終更新日: 2024-02-21)

主引用文献

Zaitseva, J.,Meneely, K.M.,Lamb, A.L.
Structure of Escherichia coli malate dehydrogenase at 1.45 A resolution.
Acta Crystallogr.,Sect.F, 65:866-869, 2009

PubMed Abstract: The structure of apo malate dehydrogenase from Escherichia coli has been determined to 1.45 A resolution. The crystals belonged to space group C2, with unit-cell parameters a = 146.0, b = 52.0, c = 168.9 A, beta = 102.2 degrees. The structure was determined with the molecular-replacement pipeline program BALBES and was refined to a final R factor of 18.6% (R(free) = 21.4%). The final model has two dimers in the asymmetric unit. In each dimer one monomer contains the active-site loop in the open conformation, whereas in the opposing monomer the active-site loop is disordered.

PubMed: 19724119
DOI: 10.1107/S1744309109032217

実験手法

X-RAY DIFFRACTION (1.45 Å)