3HHD

Structure of the Human Fatty Acid Synthase KS-MAT Didomain as a Framework for Inhibitor Design.

3HHD の概要

• エントリーDOI: 10.2210/pdb3hhd/pdb
• 分子名称: Fatty acid synthase, CHLORIDE ION (3 entities in total)
• 機能のキーワード: transferase, fatty acid synthase, multienzyme, megasynthase, fatty acid synthesis, acetylation, cytoplasm, fatty acid biosynthesis, hydrolase, lipid synthesis, lyase, multifunctional enzyme, nad, nadp, oxidoreductase, phosphopantetheine, phosphoprotein, pyridoxal phosphate
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm : P49327
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 417979.59

構造登録者

Pappenberger, G.M.,Benz, J.,Thoma, R.,Rudolph, M.G. (登録日: 2009-05-15, 公開日: 2010-02-09, 最終更新日: 2023-09-06)

• 主引用文献: Pappenberger, G.,Benz, J.,Gsell, B.,Hennig, M.,Ruf, A.,Stihle, M.,Thoma, R.,Rudolph, M.G.; Structure of the human fatty acid synthase KS-MAT didomain as a framework for inhibitor design.; J.Mol.Biol., 397:508-519, 2010; PubMed: 20132826; DOI: 10.1016/j.jmb.2010.01.066

実験手法

X-RAY DIFFRACTION (2.15 Å)