3HFC
A trimeric form of the Kv7.1 A domain Tail, L602M/L606M mutant Semet
Summary for 3HFC
Entry DOI | 10.2210/pdb3hfc/pdb |
Related | 3HFE |
Descriptor | Potassium voltage-gated channel subfamily KQT member 1 (2 entities in total) |
Functional Keywords | coiled coil, trimer, alternative splicing, atrial fibrillation, cell membrane, cytoplasmic vesicle, deafness, disease mutation, glycoprotein, ion transport, ionic channel, long qt syndrome, membrane, phosphoprotein, polymorphism, potassium, potassium channel, potassium transport, short qt syndrome, transmembrane, transport, voltage-gated channel, transport protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Multi-pass membrane protein: P51787 |
Total number of polymer chains | 3 |
Total formula weight | 10597.99 |
Authors | Xu, Q.,Minor, D.L. (deposition date: 2009-05-11, release date: 2009-09-01, Last modification date: 2021-10-13) |
Primary citation | Xu, Q.,Minor, D.L. Crystal structure of a trimeric form of the K(V)7.1 (KCNQ1) A-domain tail coiled-coil reveals structural plasticity and context dependent changes in a putative coiled-coil trimerization motif. Protein Sci., 18:2100-2114, 2009 Cited by PubMed: 19693805DOI: 10.1002/pro.224 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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