3HCV

Crystal structure of HLA-B*2709 complexed with the double citrullinated vasoactive intestinal peptide type 1 receptor (VIPR) peptide (residues 400-408)

Summary for 3HCV

• Entry DOI: 10.2210/pdb3hcv/pdb
• Related: 1of2 1ogt 3b3i 3b6s
• Descriptor: HLA class I histocompatibility antigen, B-27 alpha chain, Beta-2-microglobulin, DOUBLE CITRULLINATED VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR, ... (4 entities in total)
• Functional Keywords: immune system-complex, mhc (major histocompatibility complex) i, hla-b*2709, glycoprotein, host-virus, immune response, polymorphism, immunoglobulin domain, host-virus interaction, membrane, transmembrane, ubl conjugation, disease mutation, glycation, pyrrolidone carboxylic acid, secreted, disulfide bond, mhc i, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P03989; Secreted . Note=(Microbial infection) In the presence of M: P61769
• Total number of polymer chains: 3
• Total formula weight: 45230.22

Authors

Beltrami, A.,Gabdulkhakov, A.,Rossmann, M.,Ziegler, A.,Uchanska-Ziegler, B.,Saenger, W. (deposition date: 2009-05-06, release date: 2009-06-09, Last modification date: 2023-11-15)

• Primary citation: Beltrami, A.,Rossmann, M.,Gabdulkhakov, A.,Ziegler, A.,Uchanska-Ziegler, B.,Saenger, W.; Citrullination-and mhc polymorphism-dependent conformational changes of a self peptide; To be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)