3HC0

BHA10 IgG1 wild-type Fab - antibody directed at human LTBR

Summary for 3HC0

Related3HC3 3HC4
DescriptorIMMUNOGLOBULIN IGG1 FAB, LIGHT CHAIN, IMMUNOGLOBULIN IGG1 FAB, HEAVY CHAIN, ACETATE ION, ... (4 entities in total)
Functional Keywordsigg1 fab, bha10, immune system
Biological sourceHomo sapiens (human)
Total number of polymer chains4
Total molecular weight93355.87
Authors
Arndt, J.W.,Jordan, J.L.,Lugovskoy, A.,Wang, D. (deposition date: 2009-05-05, release date: 2009-08-04, Last modification date: 2011-07-13)
Primary citation
Jordan, J.L.,Arndt, J.W.,Hanf, K.,Li, G.,Hall, J.,Demarest, S.,Huang, F.,Wu, X.,Miller, B.,Glaser, S.,Fernandez, E.J.,Wang, D.,Lugovskoy, A.
Structural understanding of stabilization patterns in engineered bispecific Ig-like antibody molecules
Proteins, 77:832-841, 2009
PubMed: 19626705 (PDB entries with the same primary citation)
DOI: 10.1002/prot.22502
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21050.5%2.7%2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution