3HAF

Human prion protein variant V129 domain swapped dimer

Summary for 3HAF

• Entry DOI: 10.2210/pdb3haf/pdb
• Related: 3HAK
• Descriptor: Major prion protein, CADMIUM ION, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: prion, cell membrane, disease mutation, disulfide bond, glycoprotein, golgi apparatus, gpi-anchor, lipoprotein, membrane, polymorphism, membrane protein
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Lipid-anchor, GPI-anchor . Isoform 2: Cytoplasm : P04156
• Total number of polymer chains: 1
• Total formula weight: 16284.80

Authors

Lee, S.,Antony, L.,Hartmann, R.,Knaus, K.J.,Surewicz, K.,Surewicz, W.K.,Yee, V.C. (deposition date: 2009-05-01, release date: 2010-01-12, Last modification date: 2017-11-01)

• Primary citation: Lee, S.,Antony, L.,Hartmann, R.,Knaus, K.J.,Surewicz, K.,Surewicz, W.K.,Yee, V.C.; Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.; Embo J., 29:251-262, 2010; PubMed: 19927125; DOI: 10.1038/emboj.2009.333

Experimental method

X-RAY DIFFRACTION (2.26 Å)