3H9S

The complex between TCR A6 and human Class I MHC HLA-A2 with the bound Tel1p peptide

3H9S の概要

• エントリーDOI: 10.2210/pdb3h9s/pdb
• 関連するPDBエントリー: 1AO7 2GJ6 3H7B 3H9H
• 分子名称: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Tel1p peptide, ... (7 entities in total)
• 機能のキーワード: tel1p peptide, nonapeptide, mhc class i, hla-a2, tcr a6, cross-reactivity, disulfide bond, glycoprotein, host-virus interaction, immune response, membrane, mhc i, phosphoprotein, transmembrane, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01892; Secreted . Note=(Microbial infection) In the presence of M: P61769
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 94908.04

構造登録者

Borbulevych, O.Y.,Baker, B.M. (登録日: 2009-04-30, 公開日: 2010-01-12, 最終更新日: 2023-09-06)

• 主引用文献: Borbulevych, O.Y.,Piepenbrink, K.H.,Gloor, B.E.,Scott, D.R.,Sommese, R.F.,Cole, D.K.,Sewell, A.K.,Baker, B.M.; T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.; Immunity, 31:885-896, 2009; PubMed: 20064447; DOI: 10.1016/j.immuni.2009.11.003

実験手法

X-RAY DIFFRACTION (2.7 Å)