3H5C

X-Ray Structure of Protein Z-Protein Z Inhibitor Complex

3H5C の概要

• エントリーDOI: 10.2210/pdb3h5c/pdb
• 分子名称: Protein Z-dependent protease inhibitor, Vitamin K-dependent protein Z, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: protein z-protein z inhibitor complex, blood coagulation, cleavage on pair of basic residues, disulfide bond, egf-like domain, gamma-carboxyglutamic acid, glycoprotein, hydroxylation, secreted, serine protease homolog, protease inhibitor, serine protease inhibitor, hydrolase inhibitor-blood clotting complex, hydrolase inhibitor/blood clotting
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 85246.31

構造登録者

Dementiev, A.A.,Huang, X.,Olson, S.T.,Gettins, P.G.W. (登録日: 2009-04-21, 公開日: 2010-04-28, 最終更新日: 2020-07-29)

• 主引用文献: Huang, X.,Dementiev, A.,Olson, S.T.,Gettins, P.G.; Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa.; J.Biol.Chem., 285:20399-20409, 2010; PubMed: 20427285; DOI: 10.1074/jbc.M110.112748

実験手法

X-RAY DIFFRACTION (3.26 Å)