3H54
Crystal Structure of human alpha-N-acetylgalactosaminidase,complex with GalNAc
Summary for 3H54
Entry DOI | 10.2210/pdb3h54/pdb |
Related | 3H53 3H55 |
Descriptor | Alpha-N-acetylgalactosaminidase, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | glycoprotein, carbohydrate-binding protein, glycosidase, lysosomal enzyme, (beta/alpha)8 barrel, protein-ligand complex, disease mutation, disulfide bond, hydrolase, lysosome |
Biological source | Homo sapiens (Human) |
Cellular location | Lysosome: P17050 |
Total number of polymer chains | 2 |
Total formula weight | 96556.85 |
Authors | Clark, N.E.,Garman, S.C. (deposition date: 2009-04-21, release date: 2009-10-20, Last modification date: 2023-09-06) |
Primary citation | Clark, N.E.,Garman, S.C. The 1.9 a structure of human alpha-N-acetylgalactosaminidase: The molecular basis of Schindler and Kanzaki diseases J.Mol.Biol., 393:435-447, 2009 Cited by PubMed: 19683538DOI: 10.1016/j.jmb.2009.08.021 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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