3H00

Structure of the C-terminal Domain of a Putative HIV-1 gp41 Fusion Intermediate

3H00 の概要

• エントリーDOI: 10.2210/pdb3h00/pdb
• 関連するPDBエントリー: 3GWO 3H01
• 分子名称: Envelope glycoprotein gp160 (2 entities in total)
• 機能のキーワード: viral membrane fusion, hiv-1, gp41, envelope protein, neutralizing antibodies, aids, apoptosis, cell membrane, cleavage on pair of basic residues, disulfide bond, fusion protein, glycoprotein, host-virus interaction, lipoprotein, membrane, palmitate, transmembrane, viral immunoevasion, virion, viral protein
• 由来する生物種: Human immunodeficiency virus type 1 lw12.3 isolate (HIV-1)
• 細胞内の位置: Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: Q70626
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 19184.62

構造登録者

Liu, J. (登録日: 2009-04-08, 公開日: 2009-12-15, 最終更新日: 2023-09-06)

• 主引用文献: Liu, J.,Deng, Y.,Li, Q.,Dey, A.K.,Moore, J.P.,Lu, M.; Role of a putative gp41 dimerization domain in human immunodeficiency virus type 1 membrane fusion.; J.Virol., 84:201-209, 2010; PubMed: 19846514; DOI: 10.1128/JVI.01558-09

実験手法

X-RAY DIFFRACTION (2.2 Å)