3GXU
Crystal structure of Eph receptor and ephrin complex
Summary for 3GXU
Entry DOI | 10.2210/pdb3gxu/pdb |
Descriptor | Ephrin type-A receptor 4, Ephrin-B2 (3 entities in total) |
Functional Keywords | complex structure, eph, ephrin, atp-binding, glycoprotein, kinase, membrane, nucleotide-binding, phosphoprotein, receptor, transferase, transmembrane, tyrosine-protein kinase, developmental protein, differentiation, disulfide bond, host-virus interaction, neurogenesis |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Single-pass type I membrane protein (By similarity): P54764 Membrane; Single-pass type I membrane protein: P52799 |
Total number of polymer chains | 2 |
Total formula weight | 36468.37 |
Authors | Qin, H.N.,Song, J.X. (deposition date: 2009-04-03, release date: 2009-10-27, Last modification date: 2023-11-01) |
Primary citation | Qin, H.,Noberini, R.,Huan, X.,Shi, J.,Pasquale, E.B.,Song, J. Structural characterization of the EphA4-ephrin-B2 complex reveals new features enabling Eph-ephrin binding promiscuity J.Biol.Chem., 2009 Cited by PubMed: 19875447DOI: 10.1074/jbc.M109.064824 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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