3GXU

Crystal structure of Eph receptor and ephrin complex

3GXU の概要

• エントリーDOI: 10.2210/pdb3gxu/pdb
• 分子名称: Ephrin type-A receptor 4, Ephrin-B2 (3 entities in total)
• 機能のキーワード: complex structure, eph, ephrin, atp-binding, glycoprotein, kinase, membrane, nucleotide-binding, phosphoprotein, receptor, transferase, transmembrane, tyrosine-protein kinase, developmental protein, differentiation, disulfide bond, host-virus interaction, neurogenesis
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane; Single-pass type I membrane protein (By similarity): P54764; Membrane; Single-pass type I membrane protein: P52799
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 36468.37

構造登録者

Qin, H.N.,Song, J.X. (登録日: 2009-04-03, 公開日: 2009-10-27, 最終更新日: 2023-11-01)

• 主引用文献: Qin, H.,Noberini, R.,Huan, X.,Shi, J.,Pasquale, E.B.,Song, J.; Structural characterization of the EphA4-ephrin-B2 complex reveals new features enabling Eph-ephrin binding promiscuity; J.Biol.Chem., 2009; PubMed: 19875447; DOI: 10.1074/jbc.M109.064824

実験手法

X-RAY DIFFRACTION (2.5 Å)