Summary for 3GWS
| Entry DOI | 10.2210/pdb3gws/pdb |
| Related | 2H77 2H79 |
| Descriptor | Thyroid hormone receptor beta, 3,5,3'TRIIODOTHYRONINE (3 entities in total) |
| Functional Keywords | thyroid hormone receptor, t3, hinge, alternative splicing, deafness, disease mutation, dna-binding, metal-binding, nucleus, polymorphism, receptor, transcription, transcription regulation, zinc, zinc-finger, hormone activator |
| Biological source | Homo sapiens (Human) |
| Cellular location | Nucleus: P10828 |
| Total number of polymer chains | 1 |
| Total formula weight | 30258.83 |
| Authors | Nascimento, A.S.,Dias, S.M.G.,Nunes, F.M.,Aparicio, R.,Polikarpov, I.,Baxter, J.D.,Webb, P. (deposition date: 2009-04-01, release date: 2009-04-28, Last modification date: 2023-11-15) |
| Primary citation | Nascimento, A.S.,Dias, S.M.G.,Nunes, F.M.,Aparicio, R.,Ambrosio, A.L.B.,Bleicher, L.,Figueira, A.C.M.,Santos, M.A.M.,de Oliveira Neto, M.,Fischer, H.,Togashi, M.,Craievich, A.F.,Garratt, R.C.,Baxter, J.D.,Webb, P.,Polikarpov, I. Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function J.Mol.Biol., 360:586-598, 2006 Cited by PubMed: 16781732DOI: 10.1016/j.jmb.2006.05.008 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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