3GV8

Human DNA polymerase iota in complex with T template DNA and incoming dGTP

3GV8 の概要

• エントリーDOI: 10.2210/pdb3gv8/pdb
• 関連するPDBエントリー: 3GV5 3GV7
• 分子名称: DNA polymerase iota, 5'-D(*AP*TP*GP*GP*GP*TP*CP*CP*T)-3', 5'-D(*AP*GP*GP*AP*CP*CP*C)-3', ... (6 entities in total)
• 機能のキーワード: y-family polymerase, polymerase iota, error prone replication, dna damage, dna repair, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, magnesium, metal-binding, mutator protein, nucleotidyltransferase, nucleus, schiff base, transferase, transferase-dna complex, transferase/dna
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Nucleus : Q9UNA4
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 52437.36

構造登録者

Kirouac, K.N.,Ling, H. (登録日: 2009-03-30, 公開日: 2009-06-02, 最終更新日: 2024-02-21)

• 主引用文献: Kirouac, K.N.,Ling, H.; Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase iota; Embo J., 28:1644-1654, 2009; PubMed: 19440206; DOI: 10.1038/emboj.2009.122

実験手法

X-RAY DIFFRACTION (2 Å)