3GV7
Human DNA polymerase iota in complex with T template DNA and incoming dTTP
Summary for 3GV7
Entry DOI | 10.2210/pdb3gv7/pdb |
Related | 3GV5 3GV8 |
Descriptor | DNA polymerase iota, 5'-D(P*AP*TP*GP*GP*GP*TP*CP*CP*T)-3', 5'-D(*AP*GP*GP*AP*CP*CP*C)-3', ... (6 entities in total) |
Functional Keywords | y-family polymerase, polymerase iota, error prone replication, dna damage, dna repair, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, magnesium, metal-binding, mutator protein, nucleotidyltransferase, nucleus, schiff base, transferase, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus: Q9UNA4 |
Total number of polymer chains | 3 |
Total formula weight | 52412.34 |
Authors | Kirouac, K.N.,Ling, H. (deposition date: 2009-03-30, release date: 2009-06-02, Last modification date: 2024-02-21) |
Primary citation | Kirouac, K.N.,Ling, H. Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase iota Embo J., 28:1644-1654, 2009 Cited by PubMed: 19440206DOI: 10.1038/emboj.2009.122 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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