3GSM

Vibrio cholerae family 3 glycoside hydrolase (NagZ) bound to N-Valeryl-PUGNAc

3GSM の概要

• エントリーDOI: 10.2210/pdb3gsm/pdb
• 関連するPDBエントリー: 2OXN 3GS6
• 分子名称: Beta-hexosaminidase, [[(3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(pentanoylamino)oxan-2-ylidene]amino] N-phenylcarbamate, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: glycoside hydrolases, cell cycle, cell division, cell shape, cell wall biogenesis/degradation, glycosidase, hydrolase, peptidoglycan synthesis
• 由来する生物種: Vibrio cholerae
• 細胞内の位置: Cytoplasm (By similarity): Q9KU37
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 38294.44

構造登録者

Balcewich, M.D.,Mark, B.L. (登録日: 2009-03-27, 公開日: 2009-06-30, 最終更新日: 2023-09-06)

• 主引用文献: Balcewich, M.D.,Stubbs, K.A.,He, Y.,James, T.W.,Davies, G.J.,Vocadlo, D.J.,Mark, B.L.; Insight into a strategy for attenuating AmpC-mediated beta-lactam resistance: structural basis for selective inhibition of the glycoside hydrolase NagZ.; Protein Sci., 18:1541-1551, 2009; PubMed: 19499593; DOI: 10.1002/pro.137

実験手法

X-RAY DIFFRACTION (2.4 Å)