3GPE

Crystal Structure Analysis of PKC (alpha)-C2 domain complexed with Ca2+ and PtdIns(4,5)P2

3GPE の概要

• エントリーDOI: 10.2210/pdb3gpe/pdb
• 関連するPDBエントリー: 1dsy 1gmi
• 分子名称: Protein kinase C alpha type, CALCIUM ION, PHOSPHATE ION, ... (5 entities in total)
• 機能のキーワード: calcium/phospholipid binding domain, c2 domain, phosphatidil serine, protein kinase, atp-binding, kinase, metal-binding, nucleotide-binding, phorbol-ester binding, phosphoprotein, serine/threonine-protein kinase, transferase, zinc-finger, signaling protein
• 由来する生物種: Rattus norvegicus (brown rat,rat,rats)
• 細胞内の位置: Cytoplasm: P05696
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17307.55

構造登録者

Ferrer-Orta, C.,Querol-Audi, J.,Fita, I.,Verdaguer, N. (登録日: 2009-03-23, 公開日: 2009-05-05, 最終更新日: 2024-04-03)

• 主引用文献: Guerrero-Valero, M.,Ferrer-Orta, C.,Querol-Audi, J.,Marin-Vicente, C.,Fita, I.,Gomez-Fernandez, J.C.,Verdaguer, N.,Corbalan-Garcia, S.; Structural and mechanistic insights into the association of PKCalpha-C2 domain to PtdIns(4,5)P2.; Proc.Natl.Acad.Sci.USA, 106:6603-6607, 2009; PubMed: 19346474; DOI: 10.1073/pnas.0813099106

実験手法

X-RAY DIFFRACTION (2 Å)