3GNI

Structure of STRAD and MO25

Summary for 3GNI

• Entry DOI: 10.2210/pdb3gni/pdb
• Related: 1UPK 1UPL
• Descriptor: Protein Mo25, STRAD alpha, CITRIC ACID, ... (5 entities in total)
• Functional Keywords: kinase fold, pseudokinase, alpha helical repeat protein, adaptor protein, atp-binding, cell cycle, kinase, nucleotide-binding, nucleus, phosphoprotein, transferase, metal binding protein-transferase complex, signaling protein-signaling protein complex, signaling protein/signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm (Potential): Q9Y376; Nucleus: Q7RTN6
• Total number of polymer chains: 2
• Total formula weight: 84384.86

Authors

Zeqiraj, E.,Goldie, S.,Alessi, D.R.,van Aalten, D.M.F. (deposition date: 2009-03-17, release date: 2009-06-16, Last modification date: 2023-09-06)

• Primary citation: Zeqiraj, E.,Filippi, B.M.,Goldie, S.,Navratilova, I.,Boudeau, J.,Deak, M.,Alessi, D.R.,van Aalten, D.M.; ATP and MO25alpha regulate the conformational state of the STRADalpha pseudokinase and activation of the LKB1 tumour suppressor; Plos Biol., 7:e1000126-e1000126, 2009; PubMed: 19513107; DOI: 10.1371/journal.pbio.1000126

Experimental method

X-RAY DIFFRACTION (2.35 Å)