3GLS
Crystal Structure of Human SIRT3
Summary for 3GLS
Entry DOI | 10.2210/pdb3gls/pdb |
Related | 3GLR 3GLT 3GLU |
Descriptor | NAD-dependent deacetylase sirtuin-3, mitochondrial, ZINC ION, TRIETHYLENE GLYCOL, ... (5 entities in total) |
Functional Keywords | nad dependent deacetylase, sirtuin, apo structure, hydrolase, metal-binding, mitochondrion, nad, polymorphism, transit peptide, zinc |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion matrix: Q9NTG7 |
Total number of polymer chains | 6 |
Total formula weight | 190462.95 |
Authors | Jin, L.,Wei, W.,Jiang, Y.,Peng, H.,Cai, J.,Mao, C.,Dai, H.,Bemis, J.E.,Jirousek, M.R.,Milne, J.C.,Westphal, C.H.,Perni, R.B. (deposition date: 2009-03-12, release date: 2009-06-16, Last modification date: 2023-09-06) |
Primary citation | Jin, L.,Wei, W.,Jiang, Y.,Peng, H.,Cai, J.,Mao, C.,Dai, H.,Choy, W.,Bemis, J.E.,Jirousek, M.R.,Milne, J.C.,Westphal, C.H.,Perni, R.B. Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes. J.Biol.Chem., 284:24394-24405, 2009 Cited by PubMed: 19535340DOI: 10.1074/jbc.M109.014928 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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