3GLS

Crystal Structure of Human SIRT3

Summary for 3GLS

Entry DOI	10.2210/pdb3gls/pdb
Related	3GLR 3GLT 3GLU
Descriptor	NAD-dependent deacetylase sirtuin-3, mitochondrial, ZINC ION, TRIETHYLENE GLYCOL, ... (5 entities in total)
Functional Keywords	nad dependent deacetylase, sirtuin, apo structure, hydrolase, metal-binding, mitochondrion, nad, polymorphism, transit peptide, zinc
Biological source	Homo sapiens (human)
Cellular location	Mitochondrion matrix: Q9NTG7
Total number of polymer chains	6
Total formula weight	190462.95
Authors	Jin, L.,Wei, W.,Jiang, Y.,Peng, H.,Cai, J.,Mao, C.,Dai, H.,Bemis, J.E.,Jirousek, M.R.,Milne, J.C.,Westphal, C.H.,Perni, R.B. (deposition date: 2009-03-12, release date: 2009-06-16, Last modification date: 2023-09-06)
Primary citation	Jin, L.,Wei, W.,Jiang, Y.,Peng, H.,Cai, J.,Mao, C.,Dai, H.,Choy, W.,Bemis, J.E.,Jirousek, M.R.,Milne, J.C.,Westphal, C.H.,Perni, R.B. Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes. J.Biol.Chem., 284:24394-24405, 2009 Cited by PubMed: 19535340 DOI: 10.1074/jbc.M109.014928 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation