3GJS

Caspase-3 Binds Diverse P4 Residues in Peptides

Summary for 3GJS

• Entry DOI: 10.2210/pdb3gjs/pdb
• Related: 3GJQ 3GJR 3GJT
• Descriptor: Caspase-3 subunit p17, Caspase-3 subunit p12, Ac-YVAD-Cho inhibitor, ... (4 entities in total)
• Functional Keywords: enzyme catalysis, cysteine protease, protein recognition, apoptosis, hydrolase, phosphoprotein, protease, s-nitrosylation, thiol protease, zymogen
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P42574 P42574
• Total number of polymer chains: 6
• Total formula weight: 59715.85

Authors

Fang, B.,Fu, G.,Agniswamy, J.,Harrison, R.W.,Weber, I.T. (deposition date: 2009-03-09, release date: 2009-03-24, Last modification date: 2011-08-17)

• Primary citation: Fang, B.,Fu, G.,Agniswamy, J.,Harrison, R.W.,Weber, I.T.; Caspase-3 binds diverse P4 residues in peptides as revealed by crystallography and structural modeling.; Apoptosis, 14:741-752, 2009; PubMed: 19283487; DOI: 10.1007/s10495-009-0333-y

Experimental method

X-RAY DIFFRACTION (1.9 Å)