3GJF

Rational development of high-affinity T-cell receptor-like antibodies

3GJF の概要

• エントリーDOI: 10.2210/pdb3gjf/pdb
• 関連するPDBエントリー: 3GJE 3GJG
• 分子名称: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, NYESO-1 peptide, ... (6 entities in total)
• 機能のキーワード: mhc, antibody, disulfide bond, glycoprotein, host-virus interaction, immune response, membrane, mhc i, phosphoprotein, polymorphism, transmembrane, ubl conjugation, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01892; Secreted: P61769
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 181421.65

構造登録者

Stewart-Jones, G.,Wadle, A.,Hombach, A.,Shenderov, E.,Held, G.,Fischer, E.,Kleber, S.,Stenner-Liewen, F.,Bauer, S.,McMichael, A.,Knuth, A.,Abken, H.,Hombach, A.A.,Cerundolo, V.,Jones, E.Y.,Renner, C. (登録日: 2009-03-08, 公開日: 2009-04-28, 最終更新日: 2023-11-01)

• 主引用文献: Stewart-Jones, G.,Wadle, A.,Hombach, A.,Shenderov, E.,Held, G.,Fischer, E.,Kleber, S.,Stenner-Liewen, F.,Bauer, S.,McMichael, A.,Knuth, A.,Abken, H.,Hombach, A.A.,Cerundolo, V.,Jones, E.Y.,Renner, C.; Rational development of high-affinity T-cell receptor-like antibodies; Proc.Natl.Acad.Sci.USA, 106:5784-5788, 2009; PubMed: 19307587; DOI: 10.1073/pnas.0901425106

実験手法

X-RAY DIFFRACTION (1.9 Å)