3GIJ

Dpo4 extension ternary complex with oxoG(syn)-A(anti) and oxoG(anti)-A(syn) pairs

3GIJ の概要

• エントリーDOI: 10.2210/pdb3gij/pdb
• 関連するPDBエントリー: 2ASD 2ASJ 2ASL 3GII 3GIK 3GIL 3GIM
• 分子名称: DNA polymerase IV, 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(2DA))-3', 5'-D(*CP*TP*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*C)-3', ... (6 entities in total)
• 機能のキーワード: dna polymerase, 8-oxoguanine, y-family, lesion bypass, dna damage, dna repair, dna replication, dna-binding, dna-directed dna polymerase, magnesium, metal-binding, mutator protein, nucleotidyltransferase, transferase, transferase-dna complex, transferase/dna
• 由来する生物種: Sulfolobus solfataricus P2; 詳細
• 細胞内の位置: Cytoplasm (Probable): Q97W02
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 98097.97

構造登録者

Rechkoblit, O.,Malinina, L.,Patel, D.J. (登録日: 2009-03-05, 公開日: 2009-05-19, 最終更新日: 2023-09-06)

• 主引用文献: Rechkoblit, O.,Malinina, L.,Cheng, Y.,Geacintov, N.E.,Broyde, S.,Patel, D.J.; Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.; Structure, 17:725-736, 2009; PubMed: 19446528; DOI: 10.1016/j.str.2009.03.011

実験手法

X-RAY DIFFRACTION (2.4 Å)