3GHB

Crystal structure of anti-HIV-1 Fab 447-52D in complex with V3 peptide W2RW020

Summary for 3GHB

• Entry DOI: 10.2210/pdb3ghb/pdb
• Related: 1Q1J 3C2A 3GHE
• Descriptor: Fab 447-52D, light chain, Fab 447-52D, heavy chain, Envelope glycoprotein, ... (5 entities in total)
• Functional Keywords: hiv, v3 loop, antibody-antigen interactions, envelope protein, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 98023.44

Authors

Kong, X.P.,Burke, V.J. (deposition date: 2009-03-03, release date: 2009-12-01, Last modification date: 2023-09-06)

• Primary citation: Burke, V.,Williams, C.,Sukumaran, M.,Kim, S.S.,Li, H.,Wang, X.H.,Gorny, M.K.,Zolla-Pazner, S.,Kong, X.P.; Structural basis of the cross-reactivity of genetically related human anti-HIV-1 mAbs: implications for design of V3-based immunogens; Structure, 17:1538-1546, 2009; PubMed: 19913488; DOI: 10.1016/j.str.2009.09.012

Experimental method

X-RAY DIFFRACTION (2.25 Å)