3GH8

Crystal structure of Mus musculus iodotyrosine deiodinase (IYD) bound to FMN and di-iodotyrosine (DIT)

Summary for 3GH8

Entry DOI	10.2210/pdb3gh8/pdb
Related	3GB5 3GFD
Descriptor	Iodotyrosine dehalogenase 1, FLAVIN MONONUCLEOTIDE, 3,5-DIIODOTYROSINE, ... (5 entities in total)
Functional Keywords	iyd, iodide salvage, flavoprotein, di-iodotyrosine, dit, fmn, membrane, nadp, oxidoreductase, transmembrane
Biological source	Mus musculus (mouse)
Cellular location	Membrane; Single-pass membrane protein (By similarity): Q9DCX8
Total number of polymer chains	8
Total formula weight	247203.73
Authors	Thomas, S.R.,McTamney, P.M.,Adler, J.M.,LaRonde-LeBlanc, N.,Rokita, S.E. (deposition date: 2009-03-03, release date: 2009-05-12, Last modification date: 2023-09-06)
Primary citation	Thomas, S.R.,McTamney, P.M.,Adler, J.M.,Laronde-Leblanc, N.,Rokita, S.E. Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands. J.Biol.Chem., 284:19659-19667, 2009 Cited by PubMed: 19436071 DOI: 10.1074/jbc.M109.013458 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.61 Å)

Structure validation