3GGF
Crystal structure of human Serine/threonine-protein kinase MST4 in complex with an quinazolin
Summary for 3GGF
Entry DOI | 10.2210/pdb3ggf/pdb |
Descriptor | Serine/threonine-protein kinase MST4, CADMIUM ION, [4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILE, ... (4 entities in total) |
Functional Keywords | serine/threonine-protein kinase, structural genomics, structural genomics consortium, sgc, apoptosis, atp-binding, golgi apparatus, kinase, magnesium, metal-binding, nucleotide-binding, phosphoprotein, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : Q9P289 |
Total number of polymer chains | 2 |
Total formula weight | 69271.27 |
Authors | Chaikuad, A.,Rellos, P.,Eidarus, S.,Das, S.,Pike, A.C.W.,Sethi, R.,Fedorov, O.,Savitsky, P.,Roos, A.K.,Filippakopoulos, P.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,von Delft, F.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2009-02-27, release date: 2009-03-24, Last modification date: 2023-09-06) |
Primary citation | Record, C.J.,Chaikuad, A.,Rellos, P.,Das, S.,Pike, A.C.,Fedorov, O.,Marsden, B.D.,Knapp, S.,Lee, W.H. Structural comparison of human mammalian ste20-like kinases Plos One, 5:e11905-e11905, 2010 Cited by PubMed: 20730082DOI: 10.1371/journal.pone.0011905 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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