3GGF

Crystal structure of human Serine/threonine-protein kinase MST4 in complex with an quinazolin

3GGF の概要

• エントリーDOI: 10.2210/pdb3ggf/pdb
• 分子名称: Serine/threonine-protein kinase MST4, CADMIUM ION, [4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILE, ... (4 entities in total)
• 機能のキーワード: serine/threonine-protein kinase, structural genomics, structural genomics consortium, sgc, apoptosis, atp-binding, golgi apparatus, kinase, magnesium, metal-binding, nucleotide-binding, phosphoprotein, transferase
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Cytoplasm : Q9P289
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 69271.27

構造登録者

Chaikuad, A.,Rellos, P.,Eidarus, S.,Das, S.,Pike, A.C.W.,Sethi, R.,Fedorov, O.,Savitsky, P.,Roos, A.K.,Filippakopoulos, P.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,von Delft, F.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2009-02-27, 公開日: 2009-03-24, 最終更新日: 2023-09-06)

• 主引用文献: Record, C.J.,Chaikuad, A.,Rellos, P.,Das, S.,Pike, A.C.,Fedorov, O.,Marsden, B.D.,Knapp, S.,Lee, W.H.; Structural comparison of human mammalian ste20-like kinases; Plos One, 5:e11905-e11905, 2010; PubMed: 20730082; DOI: 10.1371/journal.pone.0011905

実験手法

X-RAY DIFFRACTION (2.35 Å)