3GCU
Human P38 MAP kinase in complex with RL48
Summary for 3GCU
Entry DOI | 10.2210/pdb3gcu/pdb |
Related | 3GCQ 3GCS |
Descriptor | Mitogen-activated protein kinase 14, 1-{3-[(6-aminoquinazolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]urea, octyl beta-D-glucopyranoside, ... (5 entities in total) |
Functional Keywords | dfg-out, type ii, atp-binding, kinase, nucleotide-binding, nucleus, phosphoprotein, serine/threonine-protein kinase, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 84916.03 |
Authors | Gruetter, C.,Simard, J.R.,Getlik, M.,Rauh, D. (deposition date: 2009-02-22, release date: 2009-06-09, Last modification date: 2023-09-06) |
Primary citation | Simard, J.R.,Getlik, M.,Grutter, C.,Pawar, V.,Wulfert, S.,Rabiller, M.,Rauh, D. Development of a fluorescent-tagged kinase assay system for the detection and characterization of allosteric kinase inhibitors. J.Am.Chem.Soc., 131:13286-13296, 2009 Cited by PubMed: 19572644DOI: 10.1021/ja902010p PDB entries with the same primary citation |
Experimental method |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)