3GCD
Structure of the V. cholerae RTX cysteine protease domain in complex with an aza-Leucine peptide inhibitor
Summary for 3GCD
Entry DOI | 10.2210/pdb3gcd/pdb |
Related PRD ID | PRD_000439 |
Descriptor | RTX toxin RtxA, ethyl (5S,8S,14S)-14-hydroxy-5,8,11-tris(2-methylpropyl)-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,11-tetraazapentadecan-15-oate, INOSITOL HEXAKISPHOSPHATE, ... (5 entities in total) |
Functional Keywords | v. cholerae, repeats-in-toxin, martx, cysteine protease, inositol hexakisphosphate, aza-peptide, aza-leu, toxin-inhibitor complex, toxin/inhibitor |
Biological source | Vibrio cholerae |
Total number of polymer chains | 4 |
Total formula weight | 95942.68 |
Authors | Lupardus, P.J.,Garcia, K.C.,Shen, A.,Bogyo, M. (deposition date: 2009-02-21, release date: 2009-05-26, Last modification date: 2023-09-06) |
Primary citation | Shen, A.,Lupardus, P.J.,Albrow, V.E.,Guzzetta, A.,Powers, J.C.,Garcia, K.C.,Bogyo, M. Mechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxin. Nat.Chem.Biol., 5:469-478, 2009 Cited by PubMed: 19465933DOI: 10.1038/nchembio.178 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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