3G4A

Crystal structure of flavine dependant thymidylate synthase S88A mutant from Thermotoga maritima at 1.95 angstrom resolution

3G4A の概要

• エントリーDOI: 10.2210/pdb3g4a/pdb
• 分子名称: Thymidylate synthase thyX, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
• 機能のキーワード: fdts, thyx, s88a mutation, dump complex, fad, flavoprotein, methyltransferase, nucleotide biosynthesis, transferase
• 由来する生物種: Thermotoga maritima MSB8
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 114325.65

構造登録者

Mathews, I.I.,Lesley, S.A.,Kohen, A. (登録日: 2009-02-03, 公開日: 2009-04-07, 最終更新日: 2024-05-22)

• 主引用文献: Koehn, E.M.,Fleischmann, T.,Conrad, J.A.,Palfey, B.A.,Lesley, S.A.,Mathews, I.I.,Kohen, A.; An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene.; Nature, 458:919-923, 2009; PubMed: 19370033; DOI: 10.1038/nature07973

実験手法

X-RAY DIFFRACTION (1.95 Å)