3G0H

Human dead-box RNA helicase DDX19, in complex with an ATP-analogue and RNA

Summary for 3G0H

• Entry DOI: 10.2210/pdb3g0h/pdb
• Related: 3EWS
• Descriptor: ATP-dependent RNA helicase DDX19B, 5'-R(P*UP*UP*UP*UP*UP*UP*U)-3', PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total)
• Functional Keywords: protein-rna complex, dbp5, structural genomics, structural genomics consortium, sgc, atp-binding, helicase, hydrolase, membrane, mrna transport, nuclear pore complex, nucleotide-binding, nucleus, phosphoprotein, protein transport, rna-binding, translocation, transport, polyuracil, hydrolase-rna complex, hydrolase/rna
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm: Q9UMR2
• Total number of polymer chains: 2
• Total formula weight: 50746.04

Authors

Karlberg, T.,Lehtio, L.,Collins, R.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Kotenyova, T.,Moche, M.,Nilsson, M.E.,Nordlund, P.,Nyman, T.,Persson, C.,Sagemark, J.,Schutz, P.,Siponen, M.I.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Welin, M.,Wisniewska, M.,Schuler, H.,Structural Genomics Consortium (SGC) (deposition date: 2009-01-28, release date: 2009-02-17, Last modification date: 2023-09-06)

• Primary citation: Collins, R.,Karlberg, T.,Lehtio, L.,Schutz, P.,van den Berg, S.,Dahlgren, L.G.,Hammarstrom, M.,Weigelt, J.,Schuler, H.; The DEXD/H-box RNA Helicase DDX19 Is Regulated by an {alpha}-Helical Switch.; J.Biol.Chem., 284:10296-10300, 2009; PubMed: 19244245; DOI: 10.1074/jbc.C900018200

Experimental method

X-RAY DIFFRACTION (2.7 Å)