3G0H

Human dead-box RNA helicase DDX19, in complex with an ATP-analogue and RNA

3G0H の概要

• エントリーDOI: 10.2210/pdb3g0h/pdb
• 関連するPDBエントリー: 3EWS
• 分子名称: ATP-dependent RNA helicase DDX19B, 5'-R(P*UP*UP*UP*UP*UP*UP*U)-3', PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total)
• 機能のキーワード: protein-rna complex, dbp5, structural genomics, structural genomics consortium, sgc, atp-binding, helicase, hydrolase, membrane, mrna transport, nuclear pore complex, nucleotide-binding, nucleus, phosphoprotein, protein transport, rna-binding, translocation, transport, polyuracil, hydrolase-rna complex, hydrolase/rna
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Cytoplasm: Q9UMR2
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 50746.04

構造登録者

Karlberg, T.,Lehtio, L.,Collins, R.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Kotenyova, T.,Moche, M.,Nilsson, M.E.,Nordlund, P.,Nyman, T.,Persson, C.,Sagemark, J.,Schutz, P.,Siponen, M.I.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Welin, M.,Wisniewska, M.,Schuler, H.,Structural Genomics Consortium (SGC) (登録日: 2009-01-28, 公開日: 2009-02-17, 最終更新日: 2023-09-06)

• 主引用文献: Collins, R.,Karlberg, T.,Lehtio, L.,Schutz, P.,van den Berg, S.,Dahlgren, L.G.,Hammarstrom, M.,Weigelt, J.,Schuler, H.; The DEXD/H-box RNA Helicase DDX19 Is Regulated by an {alpha}-Helical Switch.; J.Biol.Chem., 284:10296-10300, 2009; PubMed: 19244245; DOI: 10.1074/jbc.C900018200

実験手法

X-RAY DIFFRACTION (2.7 Å)