3FY1

The Acidic Mammalian Chitinase catalytic domain in complex with methylallosamidin

3FY1 の概要

• エントリーDOI: 10.2210/pdb3fy1/pdb
• 関連するPDBエントリー: 3FXY
• 分子名称: Acidic mammalian chitinase, 2-acetamido-2-deoxy-6-O-methyl-alpha-D-allopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-allopyranose, ALLOSAMIZOLINE, ... (4 entities in total)
• 機能のキーワード: chitinase, asthma, inhibitor, chitin degradation, methylallosamidin, alternative splicing, carbohydrate metabolism, chitin-binding, cytoplasm, glycosidase, hydrolase, polymorphism, polysaccharide degradation, secreted
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 89716.06

構造登録者

Olland, A.M. (登録日: 2009-01-21, 公開日: 2009-03-10, 最終更新日: 2023-09-06)

• 主引用文献: Olland, A.M.,Strand, J.,Presman, E.,Czerwinski, R.,Joseph-McCarthy, D.,Krykbaev, R.,Schlingmann, G.,Chopra, R.,Lin, L.,Fleming, M.,Kriz, R.,Stahl, M.,Somers, W.,Fitz, L.,Mosyak, L.; Triad of polar residues implicated in pH specificity of acidic mammalian chitinase.; Protein Sci., 18:569-578, 2009; PubMed: 19241384; DOI: 10.1002/pro.63

実験手法

X-RAY DIFFRACTION (1.7 Å)