3FVX
Human kynurenine aminotransferase I in complex with tris
Summary for 3FVX
| Entry DOI | 10.2210/pdb3fvx/pdb |
| Descriptor | Kynurenine--oxoglutarate transaminase 1, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SODIUM ION, ... (4 entities in total) |
| Functional Keywords | alpha beta protein plp dependent protein aminotransferase lyase pyridoxal phosphate transferase, alternative splicing, aminotransferase, cytoplasm, lyase, pyridoxal phosphate, transferase |
| Biological source | Homo sapiens (Human) |
| Cellular location | Cytoplasm: Q16773 |
| Total number of polymer chains | 2 |
| Total formula weight | 96480.12 |
| Authors | Han, Q.,Robinson, H.,Cai, T.,Tagle, D.A.,Li, J. (deposition date: 2009-01-16, release date: 2009-05-19, Last modification date: 2023-11-22) |
| Primary citation | Han, Q.,Robinson, H.,Cai, T.,Tagle, D.A.,Li, J. Structural insight into the inhibition of human kynurenine aminotransferase I/glutamine transaminase K J.Med.Chem., 52:2786-2793, 2009 Cited by PubMed: 19338303DOI: 10.1021/jm9000874 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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